OMNI Lab Publications

Sugimoto K, Chung DY, Böhm M, Fischer P, Takizawa T, Aslihan Aykan S, Qin T, Yanagisawa T, Harriott A, Oka F, Yaseen MA, Sakadžić S, Ayata C.
Peri-Infarct Hot-Zones Have Higher Susceptibility to Optogenetic Functional Activation-Induced Spreading Depolarizations.
Stroke
51
2526-35
2020

PMID: 32640946

Sencan I, Esipova T, Kiliç K, Li B, Desjardins M, Yaseen MA, Wang H, Porter JE, Kura S, Fu B, Secomb TW, Boas DA, Vinogradov SA, Devor A, Sakadžić S.
Optical measurement of microvascular oxygenation and blood flow responses in awake mouse cortex during functional activation.
J Cereb Blood Flow Metab.
2020

PMID: 32515672

Bartosik PB, Fitzgerald JE, El Khatib M, Yaseen MA, Vinogradov SA, Niedre M.
Prospects for the Use of Upconverting Nanoparticles as a Contrast Agent for Enumeration of Circulating Cells in vivo.
Int J Nanomedicine.
15
1709-19
2020

PMID: 32210561

Li B, Esipova TV, Sencan I, Kiliç K, Fu B, Desjardins M, Moeini M, Kura S, Yaseen MA, Lesage F, Østergaard L, Devor A, Boas DA, Vinogradov SA, Sakadžić S.
More homogeneous capillary flow and oxygenation in deeper cortical layers correlate with increased oxygen extraction.
Elife.
8
2019

PMID: 31305237

Xie H, Chung DY, Kura S, Sugimoto K, Aykan SA, Wu Y, Sakadžić S, Yaseen MA, Boas DA, Ayata C.
Differential effects of anesthetics on resting state functional connectivity in the mouse.
J Cereb Blood Flow Metab.
40
875-84
2020

PMID: 31092086

Böhm M, Chung DY, Gómez CA, Qin T, Takizawa T, Sadeghian H, Sugimoto K, Sakadžić S, Yaseen MA, Ayata C.
Local and remote stimulus-response characteristics, and uncoupling by spreading depression.
J Cereb Blood Flow Metab.
40
808-22
2020

PMID: 31063009

Li B, Ohtomo R, Thunemann M, Adams SR, Yang J, Fu B, Yaseen MA, Ran C, Polimeni JR, Boas DA, Devor A, Lo EH, Arai K, Sakadžić S.
Two-photon microscopic imaging of capillary red blood cell flux in mouse brain reveals vulnerability of cerebral white matter to hypoperfusion.
J Cereb Blood Flow Metab.
40
501-12
2020

PMID: 30829101

Chung DY, Sadeghian H, Qin T, Lule S, Lee H, Karakaya F, Goins S, Oka F, Yaseen MA, Houben T, Tolner EA, van den Maagdenberg AMJM, Whalen MJ, Sakadžić S, Ayata C.
Determinants of Optogenetic Cortical Spreading Depolarizations.
Cereb Cortex.
29
1150-61
2019

PMID: 29425263

Gómez CA, Fu B, Sakadžić S, Yaseen MA.
Cerebral metabolism in a mouse model of Alzheimer's disease characterized by two-photon fluorescence lifetime microscopy of intrinsic NADH.
Neurophotonics.
5
045008
2018

PMID: 30603656

Sencan I, Esipova TV, Yaseen MA, Fu B, Boas DA, Vinogradov SA, Shahidi M, Sakadžić S.
Two-photon phosphorescence lifetime microscopy of retinal capillary plexus oxygenation in mice.
J Biomed Opt.
23
1-9
2018

PMID: 30516039

Chung DY, Sugimoto K, Fischer P, Böhm M, Takizawa T, Sadeghian H, Morais A, Harriott A, Oka F, Qin T, Henninger N, Yaseen MA, Sakadžić S, Ayata C.
Real-time non-invasive in vivo visible light detection of cortical spreading depolarizations in mice.
J Neurosci Methods.
309
143-6
2018

PMID: 30194041

Gómez CA, Sutin J, Wu W, Fu B, Uhlirova H, Devor A, Boas DA, Sakadžić S, Yaseen MA.
Phasor analysis of NADH FLIM identifies pharmacological disruptions to mitochondrial metabolic processes in the rodent cerebral cortex.
PLoS One.
13
e0194578
2018

PMID: 29561904

Polasek M, Yang Y, Schühle DT, Yaseen MA, Kim YR, Sung YS, Guimaraes AR, Caravan P.
Molecular MR imaging of fibrosis in a mouse model of pancreatic cancer.
Sci Rep.
7
8114
2017

PMID: 28808290

Yaseen MA, Sutin J, Wu W, Fu B, Uhlirova H, Devor A, Boas DA, Sakadžić S.
Fluorescence lifetime microscopy of NADH distinguishes alterations in cerebral metabolism in vivo
Biomed Opt Express.
8
2368-85
2017

PMID: 28663879

Sakadžić S, Yaseen MA, Jaswal R, Roussakis E, Dale AM, Buxton RB, Vinogradov SA, Boas DA, Devor A.
Two-photon microscopy measurement of cerebral metabolic rate of oxygen using periarteriolar oxygen concentration gradients.
Neurophotonics.
3
045005
2016

PMID: 27774493

Uhlirova H, Kiliç K, Tian P, Sakadžić S, Gagnon L, Thunemann M, Desjardins M, Saisan PA, Nizar K, Yaseen MA, Hagler DJ, Vandenberghe M, Djurovic S, Andreassen OA, Silva GA, Masliah E, Kleinfeld D, Vinogradov S, Buxton RB, Einevoll GT, Boas DA, Dale AM, Devor A.
The roadmap for estimation of cell-type-specific neuronal activity from non-invasive measurements.
Philos Trans R Soc Lond B Biol Sci.
371
2016

PMID: 27574309

Wang H, Akkin T, Magnain C, Wang R, Dubb J, Kostis WJ, Yaseen MA, Cramer A, Sakadžić S, Boas D.
Polarization sensitive optical coherence microscopy for brain imaging.
Opt Lett.
41
2213-6
2016

PMID: 27176965

Yaseen MA, Srinivasan VJ, Gorczynska I, Fujimoto JG, Boas DA, Sakadžić S.
Multimodal optical imaging system for in vivo investigation of cerebral oxygen delivery and energy metabolism.
Biomed Opt Express.
6
4994-5007
2015

PMID: 26713212

Gagnon L, Sakadžić S, Lesage F, Mandeville ET, Fang Q, Yaseen MA, Boas DA.
Multimodal reconstruction of microvascular-flow distributions using combined two-photon microscopy and Doppler optical coherence tomography.
Neurophotonics.
2
015008
2015

PMID: 26157987

Gagnon L, Sakadžić S, Lesage F, Musacchia JJ, Lefebvre J, Fang Q, Yücel MA, Evans KC, Mandeville ET, Cohen-Adad J, Polimeni JR, Yaseen MA, Lo EH, Greve DN, Buxton RB, Dale AM, Devor A, Boas DA.
Quantifying the microvascular origin of BOLD-fMRI from first principles with two-photon microscopy and an oxygen-sensitive nanoprobe.
J Neurosci.
35
3663-75
2015

PMID: 25716864

Sakadžić S, Mandeville ET, Gagnon L, Musacchia JJ, Yaseen MA, Yucel MA, Lefebvre J, Lesage F, Dale AM, Eikermann-Haerter K, Ayata C, Srinivasan VJ, Lo EH, Devor A, Boas DA.
Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue.
Nat Commun.
5
5734
2014

PMID: 25483924

Zhang X, Tian Y, Yuan P, Li Y, Yaseen MA, Grutzendler J, Moore A, Ran C.
A bifunctional curcumin analogue for two-photon imaging and inhibiting crosslinking of amyloid beta in Alzheimer's disease.
Chem Commun (Camb).
50
11550-3
2014

PMID: 25134928.

Yaseen MA, Sakadžić S, Wu W, Becker W, Kasischke KA, Boas DA.
In vivo imaging of cerebral energy metabolism with two-photon fluorescence lifetime microscopy of NADH.
Biomed Opt Express.
4
307-21
2013

PMID:23412419.

Moriggi L, Yaseen MA, Helm L, Caravan P.
Serum albumin targeted, pH-dependent magnetic resonance relaxation agents.
Chemistry.
18
3675-86
2012

PMID:22328098.

Devor A, Sakadžić S, Srinivasan VJ, Yaseen MA, Nizar K, Saisan PA, Tian P, Dale AM, Vinogradov SA, Franceschini MA, Boas DA.
Frontiers in optical imaging of cerebral blood flow and metabolism.
J Cereb Blood Flow Metab.
32
1259-76
2012

PMID:22252238.

Devor A, Sakadžić S, Saisan PA, Yaseen MA, Roussakis E, Srinivasan VJ, Vinogradov SA, Rosen BR, Buxton RB, Dale AM, Boas DA.
"Overshoot" of O2 is required to maintain baseline tissue oxygenation at locations distal to blood vessels.
J Neurosci.
31
13676-81
2011

PMID:21940458.

Sakadžić S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Wu W, Devor A, Lo EH, Vinogradov SA, Boas DA.
Cerebral blood oxygenation measurement based on oxygen-dependent quenching of phosphorescence.
J Vis Exp.
4
2011

PMID:21587157.

Yaseen MA, Srinivasan VJ, Sakadžić S, Radhakrishnan H, Gorczynska I, Wu W, Fujimoto JG, Boas DA.
Microvascular oxygen tension and flow measurements in rodent cerebral cortex during baseline conditions and functional activation.
J Cereb Blood Flow Metab.
31
1051-63
2011

PMID:21179069.

Sakadžić S, Roussakis E, Yaseen MA, Mandeville ET, Srinivasan VJ, Arai K, Ruvinskaya S, Devor A, Lo EH, Vinogradov SA, Boas DA.
Two-photon high-resolution measurement of partial pressure of oxygen in cerebral vasculature and tissue.
Nat Methods.
7
755-9
2010

PMID:20693997.

Yaseen MA, Ermilov SA, Brecht HP, Su R, Conjusteau A, Fronheiser M, Bell BA, Motamedi M, Oraevsky AA.
Optoacoustic imaging of the prostate: development toward image-guided biopsy.
J Biomed Opt.
15
021310
2010

PMID:20459232.

Yu J, Javier D, Yaseen MA, Nitin N, Richards-Kortum R, Anvari B, Wong MS.
Self-assembly synthesis, tumor cell targeting, and photothermal capabilities of antibody-coated indocyanine green nanocapsules.
J Am Chem Soc.
132
1929-38
2010

PMID:20092330.

Sukhotinsky I, Yaseen MA, Sakadžić S, Ruvinskaya S, Sims JR, Boas DA, Moskowitz MA, Ayata C.
Perfusion pressure-dependent recovery of cortical spreading depression is independent of tissue oxygenation over a wide physiologic range.
J Cereb Blood Flow Metab.
30
1168-77
2010

PMID:20087371.

Yaseen MA, Srinivasan VJ, Sakadžić S, Wu W, Ruvinskaya S, Vinogradov SA, Boas DA.
Optical monitoring of oxygen tension in cortical microvessels with confocal microscopy.
Opt Express.
17
22341-50
2009

PMID:20052157.

Yaseen MA, Yu J, Jung B, Wong MS, Anvari B.
Biodistribution of encapsulated indocyanine green in healthy mice.
Mol Pharm.
6
1321-32
2009

PMID: 19799463.

Yaseen MA, Yu J, Wong MS, Anvari B.
In-vivo fluorescence imaging of mammalian organs using charge-assembled mesocapsule constructs containing indocyanine green.
Opt Express.
16
20577-87
2008

PMID:19065196.

Yaseen MA, Yu J, Wong MS, Anvari B.
Stability assessment of indocyanine green within dextran-coated mesocapsules by absorbance spectroscopy.
J Biomed Opt.
12
064031
2007

PMID:18163847.

Yaseen MA, Yu J, Wong MS, Anvari B.
Laser-induced heating of dextran-coated mesocapsules containing indocyanine green.
Biotechnol Prog.
23
1431-40
2007

PMID:17914861.

Dai T, Yaseen MA, Diagaradjane P, Chang DW, Anvari B.
Comparative study of cryogen spray cooling with R-134a and R-404a: implications for laser treatment of dark human skin.
J Biomed Opt.
11
041116
2006

PMID:16965144.

Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B.
Synchronous fluorescence spectroscopic characterization of DMBA-TPA-induced squamous cell carcinoma in mice.
J Biomed Opt.
11
014012
2006

PMID:16526889.

Diagaradjane P, Yaseen MA, Yu J, Wong MS, Anvari B.
Autofluorescence characterization for the early diagnosis of neoplastic changes in DMBA/TPA-induced mouse skin carcinogenesis.
Lasers Surg Med.
37
382-95
2005

PMID:16240416.

Dai T, Diagaradjane P, Yaseen MA, Pikkula BM, Thomsen S, Anvari B.
Laser-induced thermal injury to dermal blood vessels: analysis of wavelength (585 nm vs. 595 nm), cryogen spray cooling, and wound healing effects.
Lasers Surg Med.
37
210-8
2005

PMID:16175632.